VERTICAL TRANSMISSION OF HIV INFECTION AND SYPHILIS IN THE LAND BORDER OF BRAZIL FROM 2010 TO 2020

Name: LEONOR HENRIETTE DE LANNOY

Publication date: 01/02/2024

Examining board:

Namesort descending Role
ANA MARIA DE BRITO Examinador Externo
ANGELICA ESPINOSA BARBOSA MIRANDA Presidente
CARLOS GRAEFF TEIXEIRA Examinador Interno
CRISPIM CERUTTI JUNIOR Examinador Interno
XIMENA PAMELA DÍAZ BERMUDEZ Examinador Externo

Summary: Introduction: Vertical transmission (VT) of HIV and syphilis (congenital syphilis) are diseases that persist as a public health problem in several parts of the world, being little studied in the Brazilian land border area (FFT). Measures to prevent TV, HIV and syphilis are widely known and Brazil provides the necessary resources and technologies. The Brazilian FFT is the 3rd largest land border in the world and, for the purposes of planning and promoting regional development, the National Regional Development Policy (PNDR) established the division of the region into three major arcs: North, Central and South. Once again, borders are unique spaces, with potentialities and challenges that require differentiated programmatic public policies that take into account the specificity of the territory. Understanding the epidemiological situation of the problem in the region aims to contribute to the implementation of public policies and support the strategy to eliminate vertical transmission of HIV and congenital syphilis.
Objectives: Understand the VT of HIV infection and syphilis and analyze the provision of health services in the FFT from 2010 to 2020. Methods: A quantitative, ecological and cross-sectional study was carried out, conducted with secondary data on cases of HIV/AIDS, pregnant women with HIV, acquired syphilis (AS), syphilis in pregnant women (SG) and congenital syphilis (CS) reported in the System Information Center for Notifiable Diseases (Sinan) between 2010 and 2020, residing in border municipalities. Information from the Live Birth Information System (Sinasc), the Primary Care Health Information System (Sisab), e-Gestor and the Medication Logistics Control System (Siclom Gestãol) were also used. The variables studied were sociodemographic characteristics, prenatal and delivery data, as well as the availability of services and procedures. The detection rates of AS, GS, AIDS, HIV/AIDS infection in children under 5 years of age, HIV in pregnant women and the incidence of CS were calculated. The HIV VT rate was estimated based on the number of HIV-infected children per year of birth divided by the number of pregnant women with HIV reported according to the year of birth. Trends in detection and incidence rates were calculated for the period analyzed. Thematic maps were constructed to analyze the spatial distribution of detection rates and incidences using the Quantum GIS (Qgis) software version 2.18.6 and the spatial analysis was evaluated using the local spatial association index (LISA), calculated with the R software version x64 3.4.0.

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