Name: JOÃO GUILHERME TAVARES MARCHIORI

Publication date: 16/11/2022
Advisor:

Namesort descending Role
ANA PAULA FERREIRA NUNES Advisor *

Examining board:

Namesort descending Role
ANA PAULA FERREIRA NUNES Advisor *
CHARBEL JACOB JUNIOR External Examiner *
DEBORA DUMMER MEIRA Internal Examiner *
LAURO FERREIRA DA SILVA PINTO NETO External Examiner *
LILIANA CRUZ SPANO Internal Examiner *

Summary: Open fractures are traumatic injuries capable of fracturing a bone,
exposing it to the external environment, with consequent colonization by
microorganisms. Open fractures are associated with soft tissue injuries, the severity of which is directly related to the risk of complications, such as nonunion and infection. The goals of treatment are prevention of infection, bone healing, and restoration of function in the affected limb. These goals are most consistently achieved through adequate fracture fixation, meticulous debridement of devitalized tissue and gross contamination, administration of antibiotics, and skin coverage as soon as local conditions permit. One of the variables whose importance has been debated is the time between the occurrence of the fracture and the start of intravenous antibiotic
prophylaxis, and represents the central scope of this work.

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