FACTORS RELATED TO ADHERENCE TO ANTIRETROVIRAL TREATMENT IN SPECIALIZED SERVICE
Name: KAMILA TESSAROLO VELAME
Publication date: 28/03/2017
Advisor:
Name |
Role |
|---|---|
| CRISPIM CERUTTI JUNIOR | Advisor * |
Examining board:
| Name |
Role |
|---|---|
| ALOÍSIO FALQUETO | Internal Examiner * |
| CRISPIM CERUTTI JUNIOR | Advisor * |
| SANDRA FAGUNDES MOREIRA DA SILVA | External Examiner * |
Summary: Introduction: Compliance is one of the main variables in which the health services may intervene in order to increase the treatment efficacy. Several factors can contribute to a better compliance or guarantee its adequacy. Objective: Verify the level of compliance to the antiretroviral treatment and its associated factors. Method: Descriptive study of cross-sectional design based on data retrieved from medical records. To achieve the objective, it was used a questionnaire composed of socialdemographic and clinical informations recorded from patients aged between thirteen and fifty-nine years attended in a specialized attendance service comprising the period from 2007 to 2014. Chi-square test was performed to verify the association of the outcome with the categorical variables. Continuous variables were compared through the "Student" t test. Results: Thirteen variables were analyzed in the bivariate model, being: sex (p=0.63), age (p=0.14), age of discovery (p=0.12), skin color (p=0.03), marital status (p=0.4), level of education (p=0.03), occupation 1 (p=0.8), occupation 2 (p=0.35), way of infection (p=0.21), time since HIV diagnosis (p<0.001), AIDS case (p<0.001), viral load (p=0.04), previous history of opportunistic infection (p=0.9). From the thirteen variables analyzed in the bivariate model, six were selected for the multivariate model (p<0.20): age of discovery (p=0.12), age (p=0.14), skin color (p=0.12), level of education (p=0.03), time since HIV diagnosis (p<0.001) and AIDS case (p<0.001). Among the six variables selected for the multivariate model, it remained significant being a case of aids (p<0.001). Conclusion: Having aids decreases the probability of non-compliance to the antiretroviral treatment by 92%. These results indicate that a symptomatic subject has a better compliance to the therapy.
